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Phylogeography of dengue virus serotype 4, Brazil, 2010-2011.

2012-01-01Artigo científico Acesso aberto
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dc.contributor.authorNunes, M. R. T.
dc.contributor.authorFaria, Nuno Rodrigues
dc.contributor.authorVasconcelos, H.B.
dc.contributor.authorMedeiros, D. B. A.
dc.contributor.authorde Lima, C. P. S.
dc.contributor.authorCarvalho, V. L.
dc.contributor.authorda Silva, E. V. P.
dc.contributor.authorCardoso, J.F.
dc.contributor.authorSousa Jr., E. C.
dc.contributor.authorNunes, K.N.B.
dc.contributor.authorRodrigues, S. G.
dc.contributor.authorAbecasis, Ana
dc.contributor.authorSuchard, M. A.
dc.contributor.authorLemey, Philippe
dc.contributor.authorVasconcelos, P. F. C.
dc.contributor.institutionCentro de Malária e outras Doenças Tropicais (CMDT)
dc.contributor.pblCDC - Centers for Disease Control and Prevention
dc.date.accessioned2021-05-05T22:41:23Z
dc.date.available2021-05-05T22:41:23Z
dc.date.issued2012-01-01
dc.description.abstractDengue virus serotype 4 (DENV-4) reemerged in Roraima State, Brazil, 28 years after it was last detected in the country in 1982. To study the origin and evolution of this reemergence, full-length sequences were obtained for 16 DENV-4 isolates from northern (Roraima, Amazonas, Pará States) and northeastern (Bahia State) Brazil during the 2010 and 2011 dengue virus seasons and for an isolate from the 1982 epidemic in Roraima. Spatiotemporal dynamics of DENV-4 introductions in Brazil were applied to envelope genes and full genomes by using Bayesian phylogeographic analyses. An introduction of genotype I into Brazil from Southeast Asia was confirmed, and full genome phylogeographic analyses revealed multiple introductions of DENV-4 genotype II in Brazil, providing evidence for >3 introductions of this genotype within the last decade: 2 from Venezuela to Roraima and 1 from Colombia to Amazonas. The phylogeographic analysis of full genome data has demonstrated the origins of DENV-4 throughout Brazil.en
dc.description.versionpublishersversion
dc.description.versionpublished
dc.format.extent375578
dc.identifier.doi10.3201/eid1811.120217
dc.identifier.issn1080-6059
dc.identifier.otherPURE: 182711
dc.identifier.otherPURE UUID: ffb471b0-adb4-409c-b7e1-89676db6f8d3
dc.identifier.otherresearchoutputwizard: 44410
dc.identifier.otherPubMed: 23092706
dc.identifier.otherScopus: 84867858511
dc.identifier.urihttp://hdl.handle.net/10362/117072
dc.language.isoeng
dc.peerreviewedyes
dc.subjectGenetics
dc.subjectEcology, Evolution, Behavior and Systematics
dc.subjectVirology
dc.subjectInfectious Diseases
dc.subjectSDG 3 - Good Health and Well-being
dc.titlePhylogeography of dengue virus serotype 4, Brazil, 2010-2011.en
dc.typejournal article
degois.publication.firstPage1858
degois.publication.issue11
degois.publication.lastPage1864
degois.publication.titleEmerging Infectious Diseases
degois.publication.volume18
dspace.entity.typePublication
rcaap.rightsopenAccess

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