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Graphene Oxide Thin Films with Drug Delivery Function

2022-03-30Recensão Acesso aberto
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dc.contributor.authorOliveira, Alexandra M.L.
dc.contributor.authorMachado, Mónica
dc.contributor.authorSilva, Gabriela A.
dc.contributor.authorBitoque, Diogo B.
dc.contributor.authorFerreira, Joana Tavares
dc.contributor.authorPinto, Luís Abegão
dc.contributor.authorFerreira, Quirina
dc.contributor.institutionNOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
dc.contributor.institutioniNOVA4Health - pólo NMS
dc.contributor.institutionCentro de Estudos de Doenças Crónicas (CEDOC)
dc.contributor.pblMDPI AG
dc.date.accessioned2022-04-12T22:48:21Z
dc.date.available2022-04-12T22:48:21Z
dc.date.issued2022-03-30
dc.descriptionFunding Information: Funding: Funding was obtained through the Fundação para a Ciência e Tecnologia (FCT) through the projects iNOVA4Health, Translational Medicine program—UIDB/Multi/04462/2020; UIDB/50008/2020 and PTDC/CTM-REF/2679/2020.
dc.description.abstractGraphene oxide has been used in different fields of nanomedicine as a manager of drug delivery due to its inherent physical and chemical properties that allow its use in thin films with biomedical applications. Several studies demonstrated its efficacy in the control of the amount and the timely delivery of drugs when it is incorporated in multilayer films. It has been demonstrated that oxide graphene layers are able to work as drug delivery or just to delay consecutive drug dosage, allowing the operation of time-controlled systems. This review presents the latest research developments of biomedical applications using graphene oxide as the main component of a drug delivery system, with focus on the production and characterization of films, in vitro and in vivo assays, main applications of graphene oxide biomedical devices, and its biocompatibility properties.en
dc.description.versionpublishersversion
dc.description.versionpublished
dc.format.extent1904663
dc.identifier.doi10.3390/nano12071149
dc.identifier.issn2079-4991
dc.identifier.otherPURE: 43146281
dc.identifier.otherPURE UUID: 903d0c5d-b225-476b-af08-3cb22b094123
dc.identifier.otherScopus: 85127338855
dc.identifier.otherPubMed: 35407267
dc.identifier.otherWOS: 000781308700001
dc.identifier.urihttp://hdl.handle.net/10362/136331
dc.identifier.urlhttps://www.scopus.com/pages/publications/85127338855
dc.language.isoeng
dc.peerreviewedyes
dc.subjectdrug delivery
dc.subjectgraphene oxide
dc.subjectlayer-by-layer
dc.subjectpolyelectrolyte multilayer films
dc.subjectGeneral Chemical Engineering
dc.subjectGeneral Materials Science
dc.titleGraphene Oxide Thin Films with Drug Delivery Functionen
dc.typereview
degois.publication.issue7
degois.publication.titleNanomaterials
degois.publication.volume12
dspace.entity.typePublication
rcaap.rightsopenAccess

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