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Candy cane syndrome

dc.contributor.authorRio-Tinto, Ricardo
dc.contributor.authorCanena, Jorge
dc.contributor.authorCanena, Jorge
dc.contributor.authorDevière, Jacques
dc.contributor.institutionNOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
dc.contributor.institutionCentro de Investigação em Tecnologias e Serviços de Saúde (CINTESIS)
dc.contributor.pblBaishideng Publishing Group
dc.date.accessioned2023-11-16T22:09:35Z
dc.date.available2023-11-16T22:09:35Z
dc.date.issued2023-07-16
dc.description.abstractBACKGROUND: Candy cane syndrome (CCS) is a condition that occurs following gastrectomy or gastric bypass. CCS remains underrecognized, yet its prevalence is likely to rise due to the obesity epidemic and increased use of bariatric surgery. No previous literature review on this subject has been published. AIM: To collate the current knowledge on CCS. METHODS: A literature search was conducted with PubMed and Google Scholar for studies from May 2007, until March 2023. The bibliographies of the retrieved articles were manually searched for additional relevant articles. RESULTS: Twenty-one articles were identified (135 patients). Abdominal pain, nausea/vomiting, and reflux were the most reported symptoms. Upper gastrointestinal (GI) series and endoscopy were performed for diagnosis. Surgical resection of the blind limb was performed in 13 studies with resolution of symptoms in 73%-100%. In surgical series, 9 complications were reported with no mortality. One study reported the surgical construction of a jejunal pouch with clinical success. Six studies described endoscopic approaches with 100% clinical success and no complications. In one case report, endoscopic dilation did not improve the patient's symptoms. CONCLUSION: CCS remains underrecognized due to lack of knowledge about this condition. The growth of the obesity epidemic worldwide and the increase in bariatric surgery are likely to increase its prevalence. CCS can be prevented if an elongated blind loop is avoided or if a jejunal pouch is constructed after total gastrectomy. Diagnosis should be based on symptoms, endoscopy, and upper GI series. Blind loop resection is curative but complex and associated with significant complications. Endoscopic management using different approaches to divert flow is effective and should be further explored.en
dc.description.versionpublishersversion
dc.description.versionpublished
dc.format.extent8
dc.format.extent1971376
dc.identifier.doi10.4253/wjge.v15.i7.510
dc.identifier.issn1948-5190
dc.identifier.otherPURE: 74242715
dc.identifier.otherPURE UUID: bbd8302a-a9fc-48ac-a654-72ef12ba411e
dc.identifier.otherPubMed: 37547243
dc.identifier.otherPubMedCentral: PMC10401408
dc.identifier.urihttp://hdl.handle.net/10362/160045
dc.language.isoeng
dc.peerreviewedyes
dc.subjectBlind pouch syndrome
dc.subjectCandy cane syndrome
dc.subjectEnd-to-side enteral anastomosis
dc.subjectPost-gastrectomy syndromes
dc.subjectSide-to-side enteral anastomosis
dc.subjectSDG 3 - Good Health and Well-being
dc.titleCandy cane syndromeen
dc.title.subtitleA systematic reviewen
dc.typejournal article
degois.publication.firstPage510
degois.publication.issue7
degois.publication.lastPage517
degois.publication.titleWorld Journal of Gastrointestinal Endoscopy
degois.publication.volume15
dspace.entity.typePublication
person.familyNameCanena
person.givenNameJorge
person.identifier.orcid0000-0002-2539-5876
person.identifier.ridI-1379-2015
person.identifier.scopus-author-id6507619160
rcaap.rightsopenAccess
relation.isAuthorOfPublicationc8b48309-6089-430b-834c-46b5f79108bc
relation.isAuthorOfPublication.latestForDiscoveryc8b48309-6089-430b-834c-46b5f79108bc

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