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Exposure assessment of the European adult population to deoxynivalenol

dc.contributor.authorNamorado, Sónia
dc.contributor.authorMartins, Carla
dc.contributor.authorOgura, Joana
dc.contributor.authorAssunção, Ricardo
dc.contributor.authorVasco, Elsa
dc.contributor.authorAppenzeller, Brice
dc.contributor.authorI Halldorsson, Thorhallur
dc.contributor.authorJanasik, Beata
dc.contributor.authorKolossa-Gehring, Marike
dc.contributor.authorVan Nieuwenhuyse, An
dc.contributor.authorÓlafsdóttir, Kristin
dc.contributor.authorRambaud, Loïc
dc.contributor.authorRiou, Margaux
dc.contributor.authorSilva, Susana
dc.contributor.authorWasowicz, Wojciech
dc.contributor.authorWeber, Till
dc.contributor.authorEsteban-López, Marta
dc.contributor.authorCastaño, Argelia
dc.contributor.authorGilles, Liese
dc.contributor.authorRodríguez Martin, Laura
dc.contributor.authorGovarts, Eva
dc.contributor.authorSchoeters, Greet
dc.contributor.authorViegas, Susana
dc.contributor.authorSilva, Maria João
dc.contributor.authorAlvito, Paula
dc.contributor.institutionComprehensive Health Research Centre (CHRC) - Pólo ENSP
dc.contributor.institutionCentro de Investigação em Saúde Pública (CISP/PHRC)
dc.contributor.institutionEscola Nacional de Saúde Pública (ENSP)
dc.contributor.institutionNOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
dc.contributor.pblElsevier Science B.V., Amsterdam.
dc.date.accessioned2024-12-18T17:28:21Z
dc.date.available2024-12-18T17:28:21Z
dc.date.issued2024-12
dc.descriptionFunding Information: HBM4EU has received funding from the European Union\u2019s research and innovation programme Horizon 2020 under grant agreement No. 733032. The HBM4EU Aligned Studies were co-funded by the European Union\u2019s programme Horizon 2020 through HBM4EU and by the participating countries through the co-authors organizations. Publisher Copyright: © 2024 The Authors
dc.description.abstractMycotoxins are natural toxins produced by fungi that may cause adverse health effects thus constituting a public health concern. Deoxynivalenol (DON), a mycotoxin affecting the immune system and causing intestinal disorders, was selected as a priority under the European Human Biomonitoring Initiative (HBM4EU). Urinary total DON levels (tDON) of 1270 participants from six countries were used to characterize the internal exposure of the adult European population and identify the most relevant determinants of exposure. tDON concentrations’ P50 and P95 were in the range of 0.41–10.16 µg/L (0.39–9.05 µg/g crt) and 3.25–46.58 µg/L (2.12–33.50 µg/g crt) respectively. Higher tDON levels were observed for (i) male participants from France and Germany, (ii) samples collected in spring and summer, (iii) participants with a lower educational level, (iv) participants living in rural areas, (v) individuals without a job in France and Luxembourg, while in Portugal higher exposure was observed in working individuals, (vi) individuals with higher consumption of cereals and bread. The proportion of individuals with exposure levels exceeding the HBM-GV of 23 µg/L was 12.3 %, ranging from 0.8 % to 20.7 % in the individual countries. This study on mycotoxins exposure has used post harmonized questionnaire data and validated analytical methodologies for analysis and covered countries representing the four geographical regions of Europe, having produced much needed knowledge on the exposure of the European adult population to deoxynivalenol.en
dc.description.versionpublishersversion
dc.description.versionpublished
dc.format.extent615451
dc.identifier.doi10.1016/j.foodres.2024.115281
dc.identifier.issn0963-9969
dc.identifier.otherPURE: 104181101
dc.identifier.otherPURE UUID: 0b78a8c0-a982-4c9c-b7ae-8f3a4a3117e5
dc.identifier.otherScopus: 85209113789
dc.identifier.otherWOS: 001360446800001
dc.identifier.otherORCID: /0000-0001-7930-2914/work/173063711
dc.identifier.otherPubMed: 39643334
dc.identifier.urihttp://hdl.handle.net/10362/176468
dc.identifier.urlhttps://www.scopus.com/pages/publications/85209113789
dc.language.isoeng
dc.peerreviewedyes
dc.subjectChemical exposure
dc.subjectDeoxynivalenol
dc.subjectHBM4EU
dc.subjectHuman biomonitoring
dc.subjectMycotoxins
dc.subjectRisk assessment
dc.subjectFood Science
dc.subjectSDG 3 - Good Health and Well-being
dc.titleExposure assessment of the European adult population to deoxynivalenolen
dc.title.subtitleresults from the HBM4EU aligned studiesen
dc.typejournal article
degois.publication.titleFood Research International
degois.publication.volume198
dspace.entity.typePublication
rcaap.rightsopenAccess

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