Blood pressure pattern among blood donors exposed to SARS-CoV-2 in Luanda, Angola

Background and Aims: SARS-CoV-2 infection is a public health concern. Several aspects related to the pattern of infection remain unclear. This study aimed to investigate the blood pressure pattern among blood donors exposed to SARS-CoV-2 in Luanda, Angola, a sub-Saharan African country. Methods: We performed a retrospective analysis containing 343 blood donors from December 2019 to September 2020. Parametric tests compared means while χ2 and logistic regression checked features associated with high blood pressure and were considered significant when p < 0.05. Results: The mean age of blood donors was 32.2 ± 8.81 years (ranging from 18 to 61 years) and 93% of the men's gender. Overall, 4.7% of the studied population had been exposed to SARS-CoV-2. High blood pressure prevalence increased from unexposed to exposed SARS-CoV-2 (6.7%–18.8%, p = 0.071). SARS-CoV-2 exposure increase systole (131 ± 12.2 mmHg to 136 ± 14.2 mmHg, p = 0.098), diastole (79.9 ± 9.53 mmHg to 84.2 ± 12.7 mmHg, p = 0.086), pulse in beats per minute (72.0 ± 11.1 to 73.7 ± 8.50, p = 0.553), and decrease donating time (6.31 ± 3.72 min to 5.48 ± 1.61 min, p = 0.371). Chances of having high blood pressure were high [OR: 3.20 (95% confidence interval [CI]: 0.85–12.1), p = 0.086] in exposed SARS-CoV-2. Donors exposed to SARS-CoV-2 with abnormal donation time increased from the donor up to 40 years to over 40 years (from 35.7% to 50%, p = 0.696). The mean systolic, diastolic, and pulse pressure were higher for non-O donors (p > 0.05). A significant link was observed, between the Rhesus factor and blood pressure status (p = 0.032). Conclusion: We showed important variations in blood pressure indices of the Angolan population exposed to SARS-CoV-2. Older age and non-O blood groups appear to be important biological factors for SARS-CoV-2 infection, as well as the risk of developing cardiovascular disease after or during SARS-CoV-2 exposure. Further studies assessing the impact on cardiovascular functions with ongoing or long-term SARS-CoV-2 exposure in individuals from resource-limited countries should be considered.

Descrição

Funding Information: Thanks to the research team of INIS/CISA (Manuela Galangue, Joltim Quivinja, Celestina Gaston, and Rui Van‑Dunen), Instituto Nacional de Sangue (Emiliana Lunbungululo, Eunice Manico, Alberto Sozinho, and Deodete Machado), and Clínica Girassol (Alice Teixeira, Domingos Alfredo, and Ngueza Loureiro) for the data collection, technical/administrative support, and testing. Publisher Copyright: © 2023 The Authors. Health Science Reports published by Wiley Periodicals LLC.

Palavras-chave

ABO/Rh blood groups Angola hypertension Luanda SARS-CoV-2 RA Public aspects of medicine General Medicine Cardiology and Cardiovascular Medicine Hematology Infectious Diseases Virology SDG 3 - Good Health and Well-being

URI

http://hdl.handle.net/10362/164754

DOI

10.1002/hsr2.1498

Coleções

Home collection (IHMT)

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