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The Valvular Heart Disease in Women (VHD-W) Registry

2025-10Artigo científico Acesso aberto
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dc.contributor.authorAnwer, Shehab
dc.contributor.authorPerez-Lopez, Pablo
dc.contributor.authorElzieny, Ali A
dc.contributor.authorHosseini, Naeimeh
dc.contributor.authorNeglia, Danilo
dc.contributor.authorTimoteo, Ana T
dc.contributor.authorPetersen, Steffen E
dc.contributor.authorDelgado, Victoria
dc.contributor.authorGimelli, Alessia
dc.contributor.authorAlmeida, Ana G
dc.contributor.authorGrapsa, Julia
dc.contributor.institutionNOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
dc.contributor.pblOxford University Press
dc.date.accessioned2026-04-23T12:12:02Z
dc.date.available2026-04-23T12:12:02Z
dc.date.issued2025-10
dc.description© The Author(s) 2025. Published by Oxford University Press on behalf of the European Society of Cardiology.
dc.description.abstractAIMS: Valvular heart disease is a leading cause of cardiovascular morbidity and mortality globally, with women experiencing delayed referrals, difficulties recognizing atypical symptoms, and suboptimal adherence to guideline-based therapies, resulting in worse outcomes. However, the literature identifying these disparities remains limited, underscoring the need for a comprehensive registry to address these gaps. The Valvular Heart Disease in Women Registry (VHD-W) aims to provide real-world insights into gender differences by examining treatment patterns, guideline adherence, and clinical results. METHODS AND RESULTS: The VHD-W is an international, multicenter, non-commercial, investigator-initiated, multipurpose registry endorsed by the European Association of Cardiovascular Imaging. The VHD-W involves adult patients with moderate-to-severe valvular heart disease admitted, either urgently or electively, to the cardiology inpatient service. The study aims to enrol 800 patients, balanced between genders, across more than 70 centres worldwide, over a 6-month period from the registry inception in March 2024 until the end of December 2025. Data will be collected at inpatient admission, inpatient discharge, and 1-year follow-up, including demographics, medical history, physical examination, biomarkers, echocardiography, other imaging results, and management. Conclusion The VHD-W is the first registry to focus on gender disparities in valvular heart disease in a real-world setting, aiming to fill a significant management gap that will help develop gender-specific, evidence-based guidelines for valvular heart disease.en
dc.description.versionpublishersversion
dc.description.versionpublished
dc.format.extent451039
dc.identifier.doi10.1093/ehjimp/qyaf123
dc.identifier.issn2755-9637
dc.identifier.otherPURE: 161052556
dc.identifier.otherPURE UUID: b7cd54ec-8d1b-40c8-b0b8-144ceb4c9608
dc.identifier.otherPubMed: 41357847
dc.identifier.otherPubMedCentral: PMC12679912
dc.identifier.urihttp://hdl.handle.net/10362/202499
dc.language.isoeng
dc.peerreviewedyes
dc.subjectSDG 5 - Gender Equality
dc.titleThe Valvular Heart Disease in Women (VHD-W) Registryen
dc.title.subtitlea global initiative to address gender disparities in management and outcomesen
dc.typejournal article
degois.publication.issue4
degois.publication.titleEuropean heart journal. Imaging methods and practice
degois.publication.volume3
dspace.entity.typePublication
rcaap.rightsopenAccess

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