Regulation of ABA signaling by SnRK1 protein kinases

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Regulation of plant energy signaling by components of the abscisic acid pathway

Publication . Adamo, Mattia Carmelo; González, Elena Baena

"The capacity to sense and react to fluctuations in nutrient availability is crucial for the survival of all living organisms. In eukaryotes, two highly evolutionarily conserved protein complexes, the Snf1/AMPK/SnRK1 and the TOR protein kinases, play an essential role in the control of energy homeostasis. Low-energy conditions activate the Snf1/AMPK/SnRK1 system, which thereby initiates a transcriptional and metabolic reprogramming to favor catabolic (energy producing) over anabolic (energy consuming) processes and ultimately restore energy homeostasis. One of the main targets of Snf1/AMPK/SnRK1 is the growth- promoting TOR kinase, which is inhibited in conditions of energy deficit that cannot sustain growth. Snf1/AMPK/SnRK1 and TOR constitute the Snf1/AMPK/SnRK1-TOR functional axis, which translates the cellular energy/nutritional status into growth outputs. The capacity to sense the energy status enables the Snf1/AMPK/SnRK1-TOR axis to react to a diversity of stress conditions that impinge on primary energy metabolism. (...)"

2019-10-29Tese de doutoramento

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Entidade financiadora

Fundação para a Ciência e a Tecnologia

Programa de financiamento

OE

Número da atribuição

SFRH/BD/122736/2016