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Discovery of novel autoinducer-2 receptors
Publication . Torcato, Inês Mota; Xavier, Karina Bívar
"Quorum sensing is a bacterial cell-cell communication mechanism mediated by
the production and detection of small chemical molecules named autoinducers. This
communication mechanism allows bacteria to regulate group behaviors, through
synchronization of gene expression, in response to variation in cell density and
species composition. The possibility of interfering with quorum sensing to control
bacterial behaviors is an attractive alternative to the commonly used antibiotics, to
which bacteria develop resistances. Autoinducer-2 (AI-2) mediated quorum sensing
is especially interesting as it is involved in interspecies communication in complex
biological niches, like the mammalian gut microbiota, where it was shown to affect
the bacterial species composition.(...)"
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Fundação para a Ciência e a Tecnologia
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PD
Número da atribuição
PD/BD/105736/2014
