Assunção-Luiz, Alan ViniciusFlória, Milena Jorge SimõesFerreira, Monique Maritan TheodoroBonfim, Paloma Cristinados Santos, Jennifer Thalita TarginoGonzález, Mariana Matosda Silva, Marina Teresa AuresArruda, Gustavo Viani2026-03-062026-03-0620250076-6046PURE: 155972370PURE UUID: c132b716-4a01-403e-9c9a-faa3733952a4Scopus: 105026734311http://hdl.handle.net/10362/201021Publisher Copyright: © 2025 Faculdade de Medicina de Ribeirao Preto - U.S.P.. All rights reserved.Symptoms such as fatigue, anxiety, and depression are common in cancer patients, with their etiology still unknown. In this context, this study aimed to identify the presence of these symptoms in this population during radiotherapy treatment and to investigate a possible correlation between them. The sample consisted of individuals of both sexes aged 18 years or older. Data were collected through a sociodemographic questionnaire, and symptoms were measured using the FACT-F scale for fatigue and the HADS scale for anxiety and depression. The study included 56 individuals, with an average age of 57 years, most women (64%). It was identified that 43 individuals (76.7%) presented with fatigue, 37 (66%) were considered cases of anxiety, and 30 (53.5%) of depression. Women had higher scores for all three symptoms. A higher frequency of symptoms was observed at the final stage of radiotherapy, with fatigue being particularly prevalent (95%). These findings may contribute to the proposal of innovative approaches, management, and treatment of symptoms, as they can impact treatment adherence, tumor remission, and quality of life.314140307728mulAnxietyDepressionFatigueOncologyRadiotherapyGeneral MedicineSDG 3 - Good Health and Well-beingjournal article10.11606/issn.2176-7262.rmrp.2025.226115https://www.scopus.com/pages/publications/105026734311