Medeiros, Jessica Farias DantasSantos, Leonor Maria PachecoSilva, Sindy MacielBarreto, Jorge Otávio MaiaGaldino, Johnathan Portela da SilvaVale, Eveline Fernandes NascimentoSantos Mercedes, Kary DesireeCosta, Mayara Suelirta daFleck, Juliana MichelottiAlmeida, Karine Suene MendesGinani, Verônica CortezAraújo, Wildo Navegantes deQueiroz, Diule Vieira dePacheco, Christina2026-02-202026-02-202026-011661-7827PURE: 153673344PURE UUID: 8a89e7e6-8dc0-4826-a504-ba1bb7a85dc1Scopus: 105028503053PubMed: 41595892PubMedCentral: PMC12840991http://hdl.handle.net/10362/200526Publisher Copyright: © 2026 by the authors.The One Health framework highlights the interconnectedness of human, animal, and environmental health, requiring interdisciplinary and multisectoral collaboration to address complex global health challenges. This scoping review protocol aims to guide the systematic mapping on how studies and policy initiatives have incorporated socioecological interconnections within the One Health paradigm, following the Joanna Briggs Institute guidance and the PRISMA Scr checklist. The experimental design includes searches in PubMed, Scopus, Web of Science, LILACS, Health Systems Evidence, Social Systems Evidence, and Google Scholar for the period from 2004 to 2025. The strategy, developed with librarian support and peer reviewed, includes terms in English, Portuguese, and Spanish. Pilot searches retrieved 5333 PubMed and 470 LILACS records. Eligible documents must explicitly present two or more of the six One Health dimensions: policies to strengthen health systems; antimicrobial resistance; food safety; environmental health; emerging and re-emerging zoonotic epidemics and pandemics; endemic zoonotic, neglected tropical and vector-borne diseases. A standardized tool was developed for data extraction, synthesizing in narrative, tabular, and graphical formats. The protocol’s utilization will provide comprehensive mapping of practices and policies, identifying achievements, barriers, and knowledge gaps to inform future strategies and strengthen global health governance.302443engantimicrobial resistanceenvironmental healthfood safetyone healthscoping review protocolzoonotic diseasesPollutionPublic Health, Environmental and Occupational HealthHealth, Toxicology and MutagenesisSDG 3 - Good Health and Well-beingjournal article10.3390/ijerph23010098https://www.scopus.com/pages/publications/105028503053