Fronteira, InêsSidat, MohsinMagalhães, João Paulode Barros, Fernando Passos CupertinoDelgado, António PedroCorreia, TiagoDaniel-Ribeiro, Cláudio TadeuFerrinho, Paulo2021-08-252021-08-252021-062352-7714PURE: 33028615PURE UUID: 3bc38f2e-fa6c-4f94-b1a1-9c993d3b4327Scopus: 85101336579PubMed: 33614885PubMedCentral: PMC7887445http://hdl.handle.net/10362/123082Funding Information: Paula Saraiva for the support with bibliography. Funda??o para a Ci?ncia e Tecnologia for funds to GHTM UID/04413/2020. CTDR is supported by CNPq, Brazil, through a Productivity Research Fellowship and is a ?Cientista do Nosso Estado? by Faperj, Rio de Janeiro, Brazil. Funding Information: Paula Saraiva for the support with bibliography. Fundação para a Ciência e Tecnologia for funds to GHTM UID/04413/2020 . CTDR is supported by CNPq , Brazil, through a Productivity Research Fellowship and is a “Cientista do Nosso Estado” by Faperj, Rio de Janeiro, Brazil. Publisher Copyright: © 2021 The AuthorsThe SARS-CoV-2 pandemic has affected communities, populations, and countries throughout the world. As the SARS-CoV-2 pandemic developed, the extent to which the disease interacted with already existing endemic, non-communicable and infectious diseases became evident, hence deeply influencing health outcomes. Additionally, a synergistic effect has been demonstrated also with socio-economic, cultural, and contextual determinants of health which seem to contribute to poorer health and accumulating social disadvantages. In this essay, using as a starting point the syndemic theory that translates the cumulative and intertwined factors between different epidemics, we argue that the SARS-CoV-2 is a one health issue of a syndemic nature and that the failure to acknowledge this contributes to weakened policy-making processes and public health responses and ineffective health policies and programs.71318654engCOVID-19Health in all policiesOne healthSARS-CoV-2SyndemicNCDNon Communicable DiseasesNTDneglected tropical diseasesSDGsustainable development goalshealth policyAgricultural and Biological Sciences (miscellaneous)Insect ScienceEconomics, Econometrics and Finance (miscellaneous)Business, Management and Accounting (miscellaneous)Management Information SystemsEngineering (miscellaneous)Media TechnologyInformation Systems and ManagementEnvironmental Science (miscellaneous)General Immunology and MicrobiologyGeneral Health ProfessionsGeneral MedicineGeneral NeuroscienceGeneral NursingPharmacology, Toxicology and Pharmaceutics(all)General PsychologyGeneral Social SciencesGeneral VeterinarySDG 1 - No PovertySDG 2 - Zero HungerSDG 3 - Good Health and Well-beingSDG 4 - Quality EducationSDG 5 - Gender EqualitySDG 8 - Decent Work and Economic GrowthSDG 10 - Reduced InequalitiesSDG 11 - Sustainable Cities and CommunitiesSDG 12 - Responsible Consumption and ProductionSDG 13 - Climate ActionSDG 15 - Life on LandSDG 16 - Peace, Justice and Strong InstitutionsSDG 17 - Partnerships for the Goalsreview10.1016/j.onehlt.2021.100228https://www.scopus.com/pages/publications/85101336579