Archer, MargaridaRodrigues, José2024-12-302024-12-302024-11-182024-07-05http://hdl.handle.net/10362/176871"Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis and is one of the most ancient infectious diseases known to affect mankind. In fact, still to this day, TB is one of the leading causes of death worldwide, as it is estimated that around 1.3 – 1.5 million people die from TB and 10 million new cases appear, every year. In addition, about 370,000 to 450,000 people develop multidrug-resistant TB (MDR-TB), for which the treatment regimens are longer and present lower success rates.(...)"engarabinofuranosyltransferasestuberculosissynthesistherapeuticsmembrane proteinsdoctoral thesis101805071