Insights into the epidemiology of drug-resistant Streptococcus pneumoniae and closely-related streptococci in the era of conjugate vaccines

Sá-Leão, RaquelLencastre, Hermínia deSimões, Alexandra Sofia Oliveira2015-01-162015-01-162011-122015-01http://hdl.handle.net/10362/14115In Portugal, the introduction of the seven-valent pneumococcal conjugate vaccine (PCV7) has led to significant changes in the population structure of Streptococcus pneumoniae. However, the levels of antimicrobial resistance have not decreased and have been a matter of concern. (...)engInsights into the epidemiology of drug-resistant Streptococcus pneumoniae and closely-related streptococci in the era of conjugate vaccinesdoctoral thesis