Melo, M. J.Pina, FernandoMaçanita, António L.Melo, Eurico C.Herrmann, ChristianeFörster, RolfKoch, HelmutWamhoff, Heinrich2019-07-162019-07-161992-10-010932-0776PURE: 14130222PURE UUID: 046f039e-5e9b-4561-98cf-6dc4a6afafd5Scopus: 21144480375WOS: A1992JU22600014ORCID: /0000-0001-7393-6801/work/59703605ORCID: /0000-0001-8529-6848/work/63723900http://www.scopus.com/inward/record.url?scp=21144480375&partnerID=8YFLogxKThe photodegradation of 2-(2-Furyl)-benzimidazole (Fuberidazole 1) has been reinvestigated employing advanced HPLC-UV/VIS technique and fluorescence emission and excitation spectroscopy in methanol at natural pH, in acidic medium and in aqueous solutions at pH 7 and 3, and four main products benzimidazole-2-carboxylic acid 3, its methyl ester 2, 1-methoxy benzimidazole 5, methyl 4-oxo-2-benzimidazole crotonate 7 (cis and trans isomers) besides benzimidazole 4 and 2, 2'-bibenzimidazole 6 and other side products have been isolated and characterized. The kinetics of the photodegradation process was followed independently by HPLC-UV and fluorescence emission showing a significant similarity of the curve habit; this allows to monitor a photodegradation at very low concentrations (5 • 10-5—5 • 10-6 M). The quantum yield of disappearance of Fuberidazole has been determined.75966203eng2-(2-Furyl)-benzimidazoleFluorescence EmissionFuberidazoleHPLC SeparationPhotodegradationGeneral Chemistryjournal article10.1515/znb-1992-1014https://www.scopus.com/pages/publications/21144480375