Moura, Pedro CatalãoRaposo, MariaVassilenko, Valentina2024-09-242024-09-242024-01-010009-8981PURE: 99692002PURE UUID: a4d8330d-2013-4a41-8d88-506e5002b3baScopus: 85179821153WOS: 001136076100001PubMed: 38065379http://hdl.handle.net/10362/172332Funding Information: This work was financed by Fundação para a Ciência e Tecnologia (FCT – Portugal) through the grants UIDB/04559/2020(LIBPhys), and UIDP/04559/2020(LIBPhys) and PD/BDE/150627/2020. Funding Information: The authors would like to thank Fundação para a Ciência e Tecnologia (FCT - Portugal) for financing the grants UIDB/04559/2020(LIBPhys) and UIDP/04559/2020(LIBPhys). PCM would like to thank Fundação para a Ciência e Tecnologia (FCT - Portugal) for financing the grant PD/BDE/150627/2020 from the Doctoral NOVA I4H Program. Publisher Copyright: © 2023 The Author(s)The analysis of volatile organic compounds (VOCs) from human matrices like breath, perspiration, and urine has received increasing attention from academic and medical researchers worldwide. These biological-borne VOCs molecules have characteristics that can be directly related to physiologic and pathophysiologic metabolic processes. In this work, gathers a total of 292 analytes that have been identified as potential biomarkers for the diagnosis of various non-carcinogenic diseases. Herein we review the advances in VOCs with a focus on breath biomarkers and their potential role as minimally invasive tools to improve diagnosis prognosis and therapeutic monitoring.191699802engBiomarkersBreath SamplingExhaled BreathNon-Carcinogenic DiseasesVOCsVolatile Organic CompoundsBiochemistryClinical BiochemistryBiochemistry, medicalSDG 3 - Good Health and Well-beingreview10.1016/j.cca.2023.117692https://www.scopus.com/pages/publications/85179821153