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Title: Metabolic and morphogenetic engineering of Bacillus subtilis: biotechnology for industry
Authors: Potot, Sébastien
Orientador: Henriques, Adriano O.
Schyns, Ghislain
Issue Date: Nov-2010
Publisher: Universidade Nova de Lisboa. Instituto de Tecnologia Química e Biológica
Abstract: The bacterium Bacillus subtilis plays a major role as model for Gram-positive research, and is widely used as industrial workhorse for the production of high-value enzymes and metabolites. Successful development of commercially-attractive strains and of original products is the key of innovation in microbial industry. Evolving a natural B. subtilis strain into an overproducer involves genetic engineering. In spite of a wide range of genetic tools and techniques available for B. subtilis, engineering of the metabolic pathways, with the purpose to reach industrially significant amount of products, requires a deep and specific understanding of the metabolism.(...)
Description: Dissertation presented to obtain the Ph.D. degree in “Biology” at the Institute of Chemical and Biological Technology of the New University of Lisbon
Appears in Collections:ITQB: MD - PhD Theses

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