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ITQB: Organic Synthesis : [1]

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Studies on the synthesis and uses of acylaziridines derived from enones have continued. These aziridines are prepared from simple primary amines anda suitable enone. Simple reaction of these aziridines with mild acids produces enones with alternative substitution. The aziridine group is thus a useful protecting group. We hope that these readily available compounds will allow us to resolve substituted cyclohexenones, to produce optically active starting materials for synthesis, using readily available optically pure amines.

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