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|Title: ||Hexose and pentose transport inascomycetousyeasts: an overview|
|Authors: ||Leandro, M. J.|
|Keywords: ||Yeast carbon metabolism|
Yeast transporter genes
Sugar proton symporter
|Issue Date: ||2009|
|Publisher: ||Federation of European Microbiological Societies|
|Abstract: ||The biochemical characterization of sugar uptake in yeasts started five decades ago
and led to the early production of abundant kinetic and mechanistic data.
However, the first accurate overview of the underlying sugar transporter genes
was obtained relatively late, due mainly to the genetic complexity of hexose uptake
in the model yeast Saccharomyces cerevisiae. The genomic era generated in turn a
massive amount of information, allowing the identification of a multitude of
putative sugar transporter and sensor-encoding genes in yeast genomes, many of
which are phylogenetically related. This review aims to briefly summarize our
current knowledge on the biochemical and molecular features of the transporters
of hexoses and pentoses in yeasts, when possible establishing links between
previous kinetic studies and genomic data currently available. Emphasis is given
to recent developments concerning the identification of D-xylose and L-arabinose
transporter genes, which are thought to be key players in the optimization of S.
cerevisiae strains for bioethanol production from lignocellulose hydrolysates.|
|Description: ||FEMS Yeast Research, Vol. 9, nº 4|
|Appears in Collections:||FCT: DCV - Artigos em revista internacional com arbitragem científica|
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