http://hdl.handle.net/10362/2085 2013-05-25T08:38:23Z http://hdl.handle.net/10362/9686 Title: A resiliência enquanto orientação de planeamento regional: uma abordagem integrada e aplicada à região do Alentejo Authors: Santos, Fernando Gilberto Teigão dos Description: Dissertação para obtenção do Grau de Doutor em Ciências do Ambiente pela Universidade Nova de Lisboa, Faculdade de Ciências e Tecnologia 2011-01-01T00:00:00Z http://hdl.handle.net/10362/9685 Title: Lean management implementation: a decision making framework Authors: Aurélio, Diogo Abstract: In this thesis the author proposes a thinking framework for decision makers considering the implementation of Lean Management methodologies in their industrial contex. The framework takes both internal and external context of each case into consderation. A logical order when considering Lean’s implementation is proposed, where strategic considerations should be taken first into consideration, and operational considerations after. Moreover, the framework proposes the power and leverage perspective on transactional exchange as the central factor to determine the strategic success of any implementation. Finally when it comes to operational considerations, a key thinking factor is taken into consideration, which is the potential penetration ability of Lean techniques according to the internal and external context. The framework is applied to a portuguese leading company in the molding industry that has already applied some Lean Management methodologies, which is Logoplaste. Results lead to conclusions that, not only Lean’s suitability varies according to context, but also that the potential penetration ability of Lean techniques decreases as the compliance level to Lean’s core principles increases, and that companies where Lean techniques with low penetration ability are suitable to be used, have a higher propensity to evolve into higher Lean maturity stages. Description: Submitted to the graduate faculty Universidade Nova de Lisboa – Faculdade de Ciências e Tecnologia in partial fulfillment of the requirements for the degree of Master in Industrial Engineering 2010-01-01T00:00:00Z http://hdl.handle.net/10362/9684 Title: Synthesis, characterization and applications of new schiff base fluorescent chemosensors for metal and DNA interactions: conventional and "green" approaches Authors: Pedras, Bruno André Cunha de Vallêra Jacques Abstract: The work presented in this thesis, which has as its central subject the synthesis and applications of new fluorescent chemosensors and probes, can be divided in two major groups. The first one deals with Schiff base-derived fluorescent chemosensors, with application in the detection of metal cations, and the second group concerns the development of new Ru(II) polypyridyl luminescent molecular probes for DNA. Before the description and discussion of the performed work, a general introduction is presented in Chapter I, where emphasis is put on the applications of molecular fluorescence to chemical sensing, in order to obtain a better understanding of the photophysical processes that underlie molecular recognition. This connection is made by defining concepts and giving examples when necessary. A brief mention to the studied analytes and the instrumental methods used both in developing the chemosensors and in their applications is also made. In Chapter II, two new chemosensors possessing crown ether moieties linked through a Schiff base to a bithiophene group are presented. These systems were synthesized and fully characterized, and their application in the sensing of Ni(II), Pd(II), Hg(II) and Na(I) was tested by absorption and emission spectroscopies, and MALDI-TOF MS. Chapter III describes two new pincer-type ligands, in which a thiophene unit is linked through a Schiff base either to pyrene or naphthalene chromophores. Sensing applications for Ni(II) and Pd(II) were investigated by different techniques, and solid complexes with the aforementioned metals were also synthesized. A new tripodal ligand derived from indole and containing three Schiff base groups is introduced in Chapter IV, and its complexes with Zn(II), Cu(II), Ni(II), Hg(II) and Pd(II) are also described. Metal ion titrations of the free ligand with the respective metal salts have been performed, helped by DFT calculations, in order to investigate the role of the central tertiary amine in metal coordination. The search for new luminescent molecular probes to be used in DNA binding is the subject of Chapter V, in which a new family of six Ru(II) polypyridyl complexes is synthesized. The relation between their structure and the binding mode to DNA is studied by absorption and steady-state emission spectroscopies, as well as by timeresolved experiments. Description: Dissertação apresentada para a obtenção do Grau de Doutor em Química Sustentável, especialidade de Química-Física Inorgânica, pela Universidade Nova de Lisboa, Faculdade de Ciências e Tecnologia 2011-01-01T00:00:00Z http://hdl.handle.net/10362/9683 Title: Chemical approaches to ubiquitous computing Authors: Baptista, Carlos Alberto Pinheiro Description: Dissertação apresentada para obtenção do Grau de Doutor em Química, perfil de Química Física, pela Universidade Nova de Lisboa, Faculdade de Ciências e Tecnologia 2010-01-01T00:00:00Z